What is CRESPINE® GEL PLUS?
CRESPINE® GEL PLUS is a sterile, viscoelastic, and biocompatible gel implant. It contains hyaluronic acid, a polysaccharide produced through the process of fermentation. CRESPINE® GEL PLUS is often used in the treatment of pain and joint function conditions caused by degenerative deficits. This orthopedic injection is made by BioPolymer, a leading manufacturer of hyaluronic acid gel.
BioPolymer offers two Crespine Gel products: Crespine Gel and Crespine Gel Plus (with Prilocain). An experienced and specialized medical practitioner should administer these injection products. They can provide personalized information to determine if HA treatment is a suitable therapy option for each patient. Additionally, they can advise patients on any necessary medical clarifications in advance.
What are the features and benefits of CRESPINE® GEL products?
Crespine Gel Plus offers several key benefits for patients with osteoarthritis:
- Fuss free treatment: CRESPINE® GEL PLUS is intended as a single-injection treatment.
- Biologically compatible: This injectable formula is non-toxic, non-inflammatory and non-immunizing.
- CE-certified: CRESPINE® GEL PLUS has obtained European CE Mark approval.
- Significant pain reduction: atients experience a notable decrease in pain levels.
- Improved joint function: The treatment enhances joint mobility and function.
- Quick procedure and treatment protocol convenience: The injection procedure is swift and convenient.
Additionally, patients enjoy prolonged relief from knee osteoarthritis and experience a better quality of life due to the alleviation of pain, swelling, and other symptoms.
What accessories/items come with CRESPINE® GEL PLUS?
- 1 prefilled 2 ml syringe
- 1 package insert
- 4 traceability labels
How does CRESPINE® GEL work?
When injected intra-articularly, this gel viscosupplement replenishes the altered synovial fluid in joints affected by osteoarthritis (OA). The cross-linked hyaluronic acid restores the viscoelastic properties of the synovial fluid, enhancing joint lubrication and cushioning while reducing friction between cartilage surfaces. This results in decreased pain, improved joint function, and enhanced mobility.
Patients should always consult medical professionals before undergoing any treatments. This ensures safety, product efficacy, satisfaction, and maximum procedural benefits. While Crespine Gel Plus outcomes may vary among patients, medical practitioners can help ensure symptomatic relief for those with osteoarthritis.
What are the ingredients of CRESPINE® GEL PLUS?
Among the various viscosupplementation treatments available for OA, Crespine Gel by BioPolymer distinguishes itself as a highly effective option for managing OA in the knee and hip joints. This injectable treatment features high-purity, non-animal-based hyaluronic acid (HA), providing a safe and efficacious solution for alleviating OA symptoms.
- Hyaluronic acid (1.0 mg)
- Cross-linked hyaluronic acid (14.0 mg)
- Sodium chloride (6.9 mg)
- Water for injection purposes (1.0 ml)
- Prilocainhydrochloride (3.0 mg)
Over time, the degradation of HA in synovial fluid leads to joint pain and stiffness. By increasing the viscosity and elasticity of synovial fluid, HA alleviates pain and inflammation. Crespine Gel Plus lubricates the joint, reduces friction, and possesses anti-inflammatory properties, which collectively help to relieve joint pain and enhance mobility.
How long do results last?
CRESPINE® GEL PLUS offers long-lasting pain relief for up to 12 months. However, patients must keep in mind that individual results may vary and medical professionals’ expertise and guidance can help them maximize the efficacy of this gel injection.
What is the expected recovery time for my patients?
In general, CRESPINE® GEL PLUS does not cause any downtime. The injection process is minimally invasive and unlikely to cause significant complications.
What are some important safety tips to follow when using this medical product?
Qualified medical professionals administer Crespine Gel Plus in a single treatment, using a sterile needle to inject it into the affected joint space. Typically, a 2 mL dosage per knee is used to achieve optimal results, underscoring the convenience and cost-efficiency of this treatment.
- You must not inject CRESPINE® GEL PLUS into the blood vessels (doing so may cause embolism and an occlusion of the vessels). This injection is intended for intra-articular use only.
- Inspect the packaging before use. Do not use CRESPINE® GEL PLUS if the packaging has been tampered with.
- Do not mix this product with other injectable agents.
What are the most common side effects of these products?
While discussing the regusltory agencies’ approval of Crespine Gel Plus is important, healthcare providers must also equip patients with a comprehensive understanding of the potential risks associated with the viscosupplement. The most common side effects of this gel injection are typically mild to moderate and resolve on their own.
- Mild swelling, redness, and tenderness
- Discomfort or pain
- Temporary increase in joint stiffness
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