NUCLEOFILL™ SOFT PLUS

NUCLEOFILL™ SOFT PLUS Product Name and Description

NUCLEOFILL™ SOFT PLUS is a bio-restructuring injectable gel formulated with polynucleotides for sensitive and delicate areas, such as the periorbital region. It is designed to hydrate, protect, and rejuvenate the skin while providing anti-aging benefits. This innovative solution is ideal for addressing oxidative stress, fine lines, and mild signs of aging.

• Type: Polynucleotide-based gel with high viscosity.
• Target Area: Sensitive and thin skin, such as around the eyes.
• Packaging: Pre-filled syringe (1.5 mL) with 30G needles included.

NUCLEOFILL™ SOFT PLUS Key Features and Benefits

NUCLEOFILL™ SOFT PLUS delivers targeted hydration and bio-restructuring for delicate skin, offering unique benefits.

• Hydration: Retains water molecules, deeply moisturizing sensitive areas.
• Antioxidant Action: Neutralizes free radicals, protecting skin from oxidative damage.
• Cellular Stimulation: Activates fibroblasts to promote collagen and elastin production.
• Skin Renewal: Enhances tissue repair and improves overall skin quality.
• Gentle and Safe: Specifically designed for thin, fragile skin.

NUCLEOFILL™ SOFT PLUS Composition

The formulation is carefully crafted to ensure efficacy and safety for delicate skin.

• Polynucleotide Concentration: 1.5%.
• Molecular Weight: Optimized for skin bioavailability.
• pH: 6.8–7.2, maintaining physiological compatibility.

NUCLEOFILL™ SOFT PLUS Intended Purpose / Indications

This product is ideal for improving hydration, texture, and elasticity in sensitive areas of the face.

• Primary Indications:
  • Fine lines and mild wrinkles, particularly in the periorbital region.
  • Dry or dehydrated skin needing revitalization.
  • Protection against oxidative stress and environmental damage.
• Target Areas: Under-eye area, upper eyelids, and other sensitive facial regions.

NUCLEOFILL™ SOFT PLUS Injection and Treatment Areas

NUCLEOFILL™ SOFT PLUS is intended for delicate and superficial injection zones.

• Recommended Areas:
  • Periorbital region: Under-eye hollows and crow’s feet.
  • Upper eyelids for hydration and elasticity.
• Injection Depth: Superficial dermis for targeted effects.

NUCLEOFILL™ SOFT PLUS Reconstitution and Preparation Guidelines

The product is pre-filled and ready for use, ensuring ease of application.

• Preparation Instructions:
  • Open the sterile packaging in an aseptic environment.
  • Attach the provided 30G needle to the syringe.
  • Inspect the solution for clarity before use.

NUCLEOFILL™ SOFT PLUS Administration and Dosage

Proper injection techniques ensure optimal outcomes for delicate skin areas.

• Injection Techniques:
  • Use micro-droplet or multi-point techniques for even application.
  • Gently massage the treated area post-injection to distribute the product evenly.
• Dosage:
  • Administer 0.05–0.1 mL per injection point, depending on the area.
  • Treatment sessions are spaced 2–3 weeks apart, with 3 sessions recommended for best results.

NUCLEOFILL™ SOFT PLUS Storage Instructions

Correct storage practices are essential to maintain product integrity and effectiveness.

• Store between 2–30°C in a cool, dry environment.
• Avoid freezing and exposure to sunlight.
• Use the product before the expiration date indicated on the packaging.

NUCLEOFILL™ SOFT PLUS Contraindications

This product should not be used in certain conditions to avoid complications.

• Do Not Use:
  • In patients allergic to polynucleotides or any product components.
  • On areas with active skin infections or inflammation.
  • During pregnancy or breastfeeding.
  • In individuals with autoimmune disorders or severe skin conditions.

NUCLEOFILL™ SOFT PLUS Precautions and Warnings

Adhering to safety guidelines ensures successful treatment outcomes.

• Avoid injecting into highly vascular areas or regions with thin dermal layers without caution.
• Refrain from combining with laser treatments, chemical peels, or other aesthetic procedures on the same day.
• Conduct a thorough patient history to assess risks and contraindications.

NUCLEOFILL™ SOFT PLUS Post-Treatment Care

Post-treatment care minimizes recovery time and enhances treatment results.

• Recommendations:
  • Avoid makeup application for 12 hours post-injection.
  • Refrain from excessive sun exposure, saunas, or physical activity for 48 hours.
  • Use a gentle, hydrating skincare routine, including SPF 50 sunscreen.

NUCLEOFILL™ SOFT PLUS Side Effects and Adverse Reactions

The treatment is well-tolerated, with side effects being mild and transient.

• Common Side Effects:
  • Temporary redness, swelling, or mild tenderness at the injection site.
  • Bruising or slight itching may occur but resolves within a few days.
• Rare Reactions:
  • Formation of small nodules or discoloration, typically self-limiting.

NUCLEOFILL™ SOFT PLUS Patient Eligibility

This product is ideal for individuals seeking non-invasive hydration and rejuvenation for delicate skin.

• Ideal Candidates:
  • Adults with early signs of aging or dehydrated skin in sensitive areas.
  • Those looking for a gentle, effective solution for periorbital wrinkles.
• Not recommended for individuals under 18 years or with severe skin allergies.

NUCLEOFILL™ SOFT PLUS Follow-Up and Maintenance

Regular maintenance sessions ensure prolonged results and skin health.

• Follow-Up Protocol:
  • Initial series: 3 sessions spaced every 2–3 weeks.
  • Maintenance: One session every 4–6 months, tailored to individual needs.

NUCLEOFILL™ SOFT PLUS Manufacturer and Regulatory Information

NUCLEOFILL™ SOFT PLUS is developed by Biosimil Aesthetics, a leader in polynucleotide-based solutions for skin rejuvenation.

• Certifications: CE-marked for safety and efficacy.
• Manufacturer: Biosimil Aesthetics, adhering to stringent quality standards.