HArmonyCA™

HArmonyCA™ Product Description

HArmonyCA™ is a hybrid injectable dermal filler combining hyaluronic acid (HA) and calcium hydroxyapatite (CaHA). It is designed for facial soft tissue augmentation and offers a dual-action effect: immediate lifting and long-lasting collagen stimulation. The addition of lidocaine ensures comfort during the treatment process. This filler is suitable for patients over 18 years of age and is administered into the deep dermal and sub-dermal layers.

HArmonyCA™ Key Features and Benefits

HArmonyCA™ is distinct from conventional single-agent fillers due to its dual-effect mechanism:

• Immediate lift provided by hyaluronic acid, which restores volume to aging skin.
• Gradual and long-lasting lift through collagen stimulation from calcium hydroxyapatite. Clinical studies show collagen effects lasting up to 12 months and clinical improvements potentially persisting for 1–3 years.

User satisfaction data highlights:

• 91.6% of patients reported improvement in treated areas.
• A 4.1/5 satisfaction rating was observed for treatment effectiveness and likelihood of repeat use within 19 months.

HArmonyCA™ Composition

The formulation comprises:

• Hyaluronic Acid (HA): Known for immediate volumizing and hydration.
• Calcium Hydroxyapatite (CaHA): Triggers natural collagen production for a durable lift.
• Lidocaine: Enhances patient comfort during injections.

Each syringe contains 1.25mL of product, with a recommended total volume tailored to the patient’s needs.

HArmonyCA™ Intended Purpose / Indications

HArmonyCA™ is used to:

• Address volume loss and structural support reduction in facial areas affected by aging.
• Enhance skin architecture for a rejuvenated appearance.
• Treat regions such as the cheeks, jowls, and chin, targeting areas where structural support is most needed.

HArmonyCA™ Injection and Treatment Areas

Recommended injection sites include:

• Deep dermal layers for optimal volumizing effects.
• Sub-dermal layers for collagen stimulation.

Primary treatment areas:

• Cheeks
• Jowls
• Chin

HArmonyCA™ Reconstitution and Preparation Guidelines

HArmonyCA™ comes pre-packaged in sterile syringes, ready for use. Aseptic techniques must be followed during handling to ensure product sterility. The injection process is simple, requiring no dilution or complex preparation.

HArmonyCA™ Administration and Dosage

The product is administered by trained professionals:

• Utilize a linear threading or fanning technique to ensure even distribution.
• Injection volume is based on patient-specific needs, with approximately 7.5mL used across multiple areas for optimal results.

HArmonyCA™ Storage Instructions

The product should be stored under the following conditions:

• Temperature range: 2–25°C.
• Avoid exposure to direct light or freezing conditions to maintain efficacy and safety.

HArmonyCA™ Contraindications

HArmonyCA™ should not be used in:

• Patients with known allergies to its components.
• Individuals with autoimmune diseases or active skin infections.
• Pregnant or breastfeeding women.

HArmonyCA™ Precautions and Warnings

Care must be taken to avoid intravascular injections, which can lead to serious complications. Patients should discuss all potential risks and ensure compatibility with other treatments.

HArmonyCA™ Post-Treatment Care

Patients should adhere to the following aftercare guidelines:

• Avoid makeup, direct UV exposure, and extreme temperatures for at least 24–48 hours.
• Massage treated areas if nodules appear.

HArmonyCA™ Side Effects and Adverse Reactions

Possible side effects include:

• Redness, swelling, or bruising at the injection site.
• Tenderness and itching, resolving within 48 hours. Severe or unexpected reactions should be reported to a healthcare provider or relevant regulatory bodies.

HArmonyCA™ Patient Eligibility

This product is suitable for:

• Adults over 18 years seeking facial volume restoration and collagen stimulation.
• Patients without contraindications such as allergies or ongoing infections.

HArmonyCA™ Follow-Up and Maintenance

For sustained results:

• Periodic evaluations and touch-up sessions are recommended.
• Long-term benefits, such as collagen stimulation, may reduce the need for frequent maintenance.

HArmonyCA™ Manufacturer and Regulatory Information

HArmonyCA™ is produced by Allergan Aesthetics, a division of AbbVie. It complies with CE regulations and is marketed with thorough post-marketing safety evaluations.

HArmonyCA™ FAQ

• What makes HArmonyCA™ unique?
  It combines the benefits of hyaluronic acid and calcium hydroxyapatite in a single product.
• How long do the effects last?
  HA effects are immediate, while collagen stimulation can last up to 3 years.
• Is it safe?
  Yes, when administered by trained professionals. Potential side effects are minimal and transient.