CROMA POLYPHIL™ NEXT

CROMA POLYPHIL™ NEXT Product Description

CROMA POLYPHIL™ NEXT is an advanced injectable treatment designed for skin revitalization, biostimulation, and enhanced aesthetic outcomes. It is a polynucleotide-based injectable that leverages PN-HPT® (Polynucleotides Highly Purified Technology), a cutting-edge formula engineered to improve skin quality, promote elasticity, and address various signs of aging. This product is particularly effective for improving skin structure in delicate areas and serves as a complementary procedure to other aesthetic treatments.

Key specifications:

• Formulation: Polynucleotides at a concentration of 15 mg/2 ml.
• Presentation: Pre-filled syringes of 2 ml.
• Needle: Includes two 30G ½ needles, 13 mm in size.

CROMA POLYPHIL™ NEXT Key Features and Benefits

CROMA POLYPHIL™ NEXT provides significant advantages in aesthetic dermatology:

• Hydration and Elasticity Improvement: It enhances fibroblast activity, leading to better hydration and elasticity.
• Skin Revitalization: Ideal for treating dull, tired-looking skin and improving the overall texture and tone.
• Minimally Invasive: Achieves effective results with minimal downtime.
• Synergistic Compatibility: Works seamlessly with other treatments like lasers, fillers, and peels.
• Long-Lasting Results: Clinical improvements can persist for several months with proper maintenance.

Clinical benefits:

• Reduction in fine lines and superficial wrinkles.
• Improvement in skin firmness and elasticity.
• Enhanced patient satisfaction due to noticeable rejuvenation.

CROMA POLYPHIL™ NEXT Composition

The key ingredient in CROMA POLYPHIL™ NEXT is polynucleotides (PN):

• Concentration: 15 mg/2 ml, optimized for sensitive and delicate skin.
• Polynucleotide Action: Activates fibroblasts, stimulates collagen production, and repairs damaged tissue.

This formulation ensures safe and effective results without excessive pulling or edema, making it suitable for thin, delicate skin.

CROMA POLYPHIL™ NEXT Intended Purpose / Indications

CROMA POLYPHIL™ NEXT is indicated for:

• Skin Rejuvenation: Addresses signs of aging, such as fine lines, wrinkles, and sagging skin.
• Anti-Aging Therapy: Prevents premature aging and enhances skin texture in younger patients.
• Complementary Treatment: Prepares the skin for procedures like fillers, lasers, and microneedling.
• Scars and Stretch Marks: Improves areas with high fibrous content.

CROMA POLYPHIL™ NEXT Injection and Treatment Areas

The product is designed for intradermal injections, targeting:

• Periorbital Areas: Includes the delicate eye contour region.
• Sensitive Skin Zones: Effective for thin skin areas, such as the neck and décolletage.

Recommended injection depth: Intradermal, with techniques such as serial puncture or linear retrograde application.

CROMA POLYPHIL™ NEXT Reconstitution and Preparation Guidelines

• Preparation: Ready-to-use pre-filled syringes; no dilution required.
• Aseptic Handling: Ensure all tools and the treatment area are sterile.
• Injection Protocol:
  • Dosage: 1-2 ml per session.
  • Frequency: Every 14 to 21 days.
  • Duration: 3-4 sessions for optimal results.

CROMA POLYPHIL™ NEXT Administration and Dosage

Administer 1-2 ml per session using:

• Injection Technique: Serial puncture with 0.5 to 1 cm spacing or linear retrograde.
• Professional Guidance: Must be performed by trained medical practitioners.

CROMA POLYPHIL™ NEXT Storage Instructions

Optimal storage conditions:

• Temperature Range: 2–25°C.
• Precautions: Avoid exposure to direct sunlight and freezing temperatures.

CROMA POLYPHIL™ NEXT Contraindications

CROMA POLYPHIL™ NEXT should not be used in patients with:

• Known allergies to polynucleotides or product components.
• Active skin infections or inflammation at the injection site.
• Autoimmune disorders or severe systemic illnesses.
• Pregnancy or breastfeeding.

CROMA POLYPHIL™ NEXT Precautions and Warnings

Medical practitioners must:

• Avoid intravascular injections.
• Perform a thorough patient consultation to assess suitability.
• Be cautious when combining with other treatments to prevent adverse interactions.

CROMA POLYPHIL™ NEXT Post-Treatment Care

Aftercare recommendations include:

• Avoiding makeup, UV exposure, and extreme temperatures for 48 hours post-treatment.
• Refraining from strenuous activities or sauna use immediately after the procedure.

CROMA POLYPHIL™ NEXT Side Effects and Adverse Reactions

Common side effects may include:

• Local Reactions: Redness, swelling, or mild bruising at the injection site.
• Rare Adverse Events: Severe allergic reactions, which require immediate medical attention.

Patients should report any unexpected or prolonged symptoms.

CROMA POLYPHIL™ NEXT Patient Eligibility

CROMA POLYPHIL™ NEXT is suitable for:

• Adults seeking skin rejuvenation or anti-aging solutions.
• Patients with no history of severe allergies, autoimmune disorders, or pregnancy.

CROMA POLYPHIL™ NEXT Follow-Up and Maintenance

For sustained results:

• Perform 3-4 sessions initially.
• Schedule maintenance treatments every 4-6 months based on individual needs.

CROMA POLYPHIL™ NEXT Manufacturer and Regulatory Information

Manufactured by CROMA Pharma, a leader in aesthetic medicine, with full compliance to CE marking standards. Each syringe is batch-coded for traceability.

CROMA POLYPHIL™ NEXT FAQ

1. What is CROMA POLYPHIL™ NEXT? A polynucleotide-based injectable for skin rejuvenation.
2. How long do results last? Results typically last 4-6 months, depending on the individual.
3. Are there any risks? Minimal risks include local reactions like redness and swelling.
4. Who can use it? Suitable for adults without contraindications.

CROMA POLYPHIL™ NEXT represents a versatile, minimally invasive solution for improving skin health and aesthetic appearance, catering to a wide range of patients seeking natural, rejuvenated results.